Gli Ordini sono momentaneamente Sospesi



1) Nobile V, Buonocore D, Michelotti A, Marzatico F. Anti-aging and filling efficacy of six types hyaluronic acid based dermo-cosmetic treatment: double blind, randomized clinical trial of efficacy and safety. J Cosmet Dermatol. 2014 Dec;13(4):277-87. doi: 10.1111/jocd.12120. PMID: 25399620; PMCID: PMC4371636.

2) Bukhari SNA, Roswandi NL, Waqas M, Habib H, Hussain F, Khan S, Sohail M, Ramli NA, Thu HE, Hussain Z. Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects. Int J Biol Macromol. 2018 Dec;120(Pt B):1682-1695. doi: 10.1016/j.ijbiomac.2018.09.188. Epub 2018 Oct 1. PMID: 30287361.

3) Radrezza S, Baron G, Nukala SB, Depta G, Aldini G, Carini M, D’Amato A. Advanced quantitative proteomics to evaluate molecular effects of low-molecular-weight hyaluronic acid in human dermal fibroblasts. J Pharm Biomed Anal. 2020 Jun 5;185:113199. doi: 10.1016/j.jpba.2020.113199. Epub 2020 Feb 29. PMID: 32146287.



1) Surjushe A, Vasani R, Saple DG. Aloe vera: a short review. Indian J Dermatol. 2008;53(4):163-6. doi: 10.4103/0019-5154.44785. PMID: 19882025; PMCID: PMC2763764.

2) Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice,aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract. Int J Toxicol. 2007;26 Suppl 2:1-50. doi: 10.1080/10915810701351186. PMID: 17613130.

3) Gupta, Vinay K, and Seema Malhotra. “Pharmacological attribute of Aloe vera: Revalidation through experimental and clinical studies.” Ayu vol. 33,2 (2012): 193-6. doi:10.4103/0974-8520.105237.

4) West DP, Zhu YF. Evaluation of aloe vera gel gloves in the treatment of dry skin associated with occupational exposure. Am J Infect Control. 2003 Feb;31(1):40-2. doi: 10.1067/mic.2003.12. PMID: 12548256.

5) Aloe:  Activity, Consistency, Authenticity and More – A Review. Marsh; J.M., Simmonds M.S.J. Procter  Gamble Co Cincinnati USA; Royal Botanic Gardens. Kew.Surrey UK Cosmet  & Toil  2020; 135 (4): 22-30.



1) Journal of Environmental Science and Health, Volume 50, 2015, pages 338-345.

2) Nutrients, December 2014, pages 5,839-5,852; and April 2014, pages 1,519-1,538.

3) Jaafar, Iman & Jaafar, Noor. (2019). ERUCA SATIVA LINN.: PHARMACOGNOSTICAL AND PHARMACOLOGICAL PROPERTIES AND PHARMACEUTICAL PREPARATIONS. Asian Journal of Pharmaceutical and Clinical Research. 12. 39-45.

4) Aqueous extracts of Eruca sativa leaves and methods for inhibiting growth of Gram-positive bacteria and mycoplasma, U.S. Patent Application 20200101124, Publication date: April 2, 2020, Assignee: Imam Abdulrahman Bin Faisal University.

5) Advances in Research 7(3): 1-14, 2016, Article no.AIR.26125 ISSN: 2348-0394, NLM ID: 101666096  Opuntia sp. Cactus: Biological Characteristics,Cultivation and Applications. Patrícia Maria Guedes Paiva, Igor Felipe Andrade Costa de Souza, Maria Cláudia Valério Vicalvi Costa, Andréa de Fátima Silva Santos and Luana Cassandra Breitenbach Barroso Coelho.

6) Amer M, Metwalli M. Topical liquiritin improves melasma. Int J Dermatol. 2000 Apr;39(4):299-301. doi: 10.1046/j.1365-4362.2000.00943.x. PMID: 10809983.

7) Yokota T, Nishio H, Kubota Y, Mizoguchi M. The inhibitory effect of glabridin from licorice extracts on melanogenesis and inflammation. Pigment Cell Res. 1998 Dec;11(6):355-61. doi: 10.1111/j.1600-0749.1998.tb00494.x. PMID: 9870547.

8) Bandyopadhyay, Debabrata. “Topical treatment of melasma.” Indian journal of dermatology vol. 54,4 (2009): 303-9. doi:10.4103/0019-5154.57602.



1) Overgaard Olsen L, Jemec GB. The influence of water, glycerin, paraffin oil and ethanol on skin mechanics. Acta Derm Venereol. 1993 Dec;73(6):404-6. doi: 10.2340/0001555573404406. PMID: 7906448.

2) Lodén M, Wessman W. The influence of a cream containing 20% glycerin and its vehicle on skin barrier properties. Int J Cosmet Sci. 2001 Apr;23(2):115-9. doi: 10.1046/j.1467-2494.2001.00060.x. PMID: 18498456.

3) Asian J Beauty Cosmetol. 2013; 11(4): 761-768.The Effect of Glycerin, Hyaluronic Acid and Silicone Oil on the Hydration, Moisturization and Transepidermal Water Loss in Human Skin. Seung Bin Kwon, Ghang Tai Lee, Seong Jin Choi, Na Kyeong Lee, Hyun Woo Park, Kwang Sik Lee, Kun Kook Lee, Kyu Joong Ahn, and In Sook An.



1) Lin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. Int J Mol Sci. 2017;19(1):70. Published 2017 Dec 27. doi:10.3390/ijms19010070.

2) Vaughn AR, Clark AK, Sivamani RK, Shi VY. Natural Oils for Skin-Barrier Repair: Ancient Compounds Now Backed by Modern Science. Am J Clin Dermatol. 2018 Feb;19(1):103-117. doi: 10.1007/s40257-017-0301-1. PMID: 28707186.



1) Engin KN. Alpha-tocopherol: looking beyond an antioxidant. Mol Vis. 2009;15:855-60. Epub 2009 Apr 23. PMID: 19390643; PMCID: PMC2672149.

2) Skin barrier benefits of sunflower seed oil _ Dermatology Times and Multimedia Medical (July 13,2015).



1) Sun-Yup Shim, Ji-Hyun Kim, Kang-Hee Kho, Mina Lee, Anti-inflammatory and anti-oxidative activities of lemon myrtle (Backhousia citriodora) leaf extract, Toxicology Reports, Volume 7, 2020, Pages 277-281.

2) Shim SY, Kim JH, Kho KH, Lee M. Anti-inflammatory and anti-oxidative activities of lemon myrtle (Backhousia citriodora) leaf extract. Toxicol Rep. 2020 Jan 27;7:277-281. doi: 10.1016/j. toxrep.2020.01.018. PMID: 32071880; PMCID: PMC7011016.

3) Attia, Jonven & Shortt, M. & Bégin-Lavallée, V. & Tubia, Claire & Loing, Estelle. (2017). 284 Backhousia citriodora leaf extract: A new active solution to control hyper-seborrhea for multi-ethnic skins. Journal of Investigative Dermatology. 137. S241. 10.1016/j.jid.2017.07.282.



1) Hwang E, Lee DG, Park SH, Oh MS, Kim SY. Coriander leaf extract exerts antioxidant activity and protects against UVB-induced photoaging of skin by regulation of procollagen type I and MMP-1 expression. J Med Food. 2014;17(9):985-995. doi:10.1089/jmf.2013.2999.

2) Park G, Kim HG, Kim YO, Park SH, Kim SY, Oh MS. Coriandrum sativum L. protects human keratinocytes from oxidative stress by regulating oxidative defense systems. Skin Pharmacol Physiol. 2012;25(2):93-9. doi: 10.1159/000335257. Epub 2012 Feb 1. PMID: 22301773.

3) IRCCS Humanitas Research Hospital, Coriandolo.



1) Dhanavade, Dr. Maruti & Jalkute, Dr. Chidambar & Sonawane, Kailas & Ghosh, Jai. (2011). Maruti J. Dhanavade, Chidamber B. Jalkute, K.D. Sonawane and Jai S. Ghosh (2011) Study antimicrobial activity of lemon (Citrus lemon L) peel extract. British Journal of Pharmacology and Toxicology, 2 (3):119-122. British Journal of Pharmacology and Toxicology. 2. 119-122.

2) W.M. Otang, A.J. Afolayan, Antimicrobial and antioxidant efficacy of Citrus limon L. peel extracts used for skin diseases by Xhosa tribe of Amathole District, Eastern Cape, South Africa, South African Journal of Botany, Volume 102, 2016, Pages 46-49, ISSN 0254-6299, https://doi. org/10.1016/j.sajb.2015.08.005.

3) Babilas P, Knie U, Abels C. Cosmetic and dermatologic use of alpha hydroxy acids. J Dtsch Dermatol Ges. 2012 Jul;10(7):488-91. English, German. doi: 10.1111/j.1610-0387.2012.07939.x. PMID: 22916351.



1) Sun P, Zhao L, Zhang N, Wang C, Wu W, Mehmood A, Zhang L, Ji B, Zhou F. Essential Oil and Juice from Bergamot and Sweet Orange Improve Acne Vulgaris Caused by Excessive Androgen Secretion. Mediators Inflamm. 2020 Oct 6;2020:8868107. doi: 10.1155/2020/8868107. PMID: 33082712; PMCID: PMC7559496. Jr, Shank RC, Slaga TJ, Snyder PW, Gill LJ, Heldreth B. Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics. Int J Toxicol. 2019 Sep/Oct;38(2_suppl):33S-59S. doi: 10.1177/1091581819862504. PMID: 31522650.

2) Benoit Roger, Pauline Burger, Pascal Baret, Jamal Chahboun, Stéphane Cerantola, Xavier Fernandez & Valérie Jeannot (2016) Identification of antibiotic and antiproliferative compounds in natural orange blossom water, Journal of Essential Oil Research, 28:2, 89-95, DOI: 10.1080/10412905.2015.1107646.



1) Brett J. West and Rachel A. Sabin, . Efficacy of a Morinda citrifolia Based Skin Care Regimen. Current Research Journal of Biological Sciences, (3): 310-314.

2) Khiljee T, Akhtar N. Investigation of antiaging and skin rejuvenation potential of phyto-constituents from Pyrus communis loaded topical emulgel. Pak J Pharm Sci. 2019 Jan;32(1(Supplementary)):293-300. PMID: 30829206.

3) Simitzis PE. Agro-Industrial By-Products and Their Bioactive Compounds—An Ally against Oxidative Stress and Skin Aging. Cosmetics. 2018; 5(4):58.

4) Murata K, Takahashi K, Nakamura H, Itoh K, Matsuda H. Search for skin-whitening agent from Prunus plants and the molecular targets in melanogenesis pathway of active compounds. Nat Prod Commun. 2014 Feb;9(2):185-8. PMID: 24689286.

5) Safety Assessment of Apple-derived Ingredients as Used in Cosmetics.  Status: Draft Final Report for Panel Review. Release Date: November 20, 2015. Panel Date: December 14-15, 2015.



1) Tang SC, Yang JH. Dual Effects of Alpha-Hydroxy Acids on the Skin. Molecules. 2018 Apr 10;23(4):863. doi: 10.3390/molecules23040863. PMID: 29642579; PMCID: PMC6017965.



1) Aggarwal B, Lamba HS, Pankaj Sharma A. Various Pharmacological Aspects of Cocos nucifera-A Review. American Journal of Pharmacological Sciences. 2017, 5(2):25-30.



1) Andersen FA. Final Safety Assessment for PCA and Sodium PCA. International Journal of Toxicology. 1999;18(2_suppl):25-34. doi:10.1177/109158189901800206.

2) Sodium PCA - The Dermatology Review. 0 8 . 2 7. 2 0 (



1) Herndon JH Jr, Jiang L, Kononov T, Fox T. An Open Label Clinical Trial of a Multi-Ingredient Anti-Aging Moisturizer Designed to Improve the Appearance of Facial Skin. J Drugs Dermatol. 2015 Jul;14(7):699-704. PMID: 26151786.



1) Naveed, Akhtar & Muhammad, Haji & Khan, Haji M. shoaib & Ashraf, Shoaib & Mohammad, Imran Shair & Ali, Atif. (2014). Skin Depigmentation Activity of Crocus sativus Extract Cream. Tropical Journal of Pharmaceutical Research. 13. 1803-1808. 10.4314/tjpr.v13i11.5.

2) Golmohammadzadeh S, Jaafari MR, Hosseinzadeh H. Does saffron have antisolar and moisturizing effects? Iran J Pharm Res. 2010 Spring;9(2):133-40. PMID: 24363719; PMCID: PMC3862060.



1) Hong Kong Med J 2015 Oct;21(5):417–25 | Epub 28 Aug 2015, DOI: 10.12809/hkmj144472

© Hong Kong Academy of Medicine. CC BY-NC-ND 4.0 **, Patient acceptability, efficacy, and skin biophysiology of a cream and cleanser containing lipid complex with shea butter extract versus a ceramide product for eczema, KL Hon, MD, FCCM1; YC Tsang, BSc1; NH Pong, MPhil1; Vivian WY Lee, PharmD2; NM Luk, FRCP3; CM Chow, FRCPCH1; TF Leung, FRCPCH, FAAAAI1.

2) Nisbet SJ. Skin acceptability of a cosmetic moisturizer formulation in female subjects with sensitive skin. Clin Cosmet Investig Dermatol. 2018 Apr 30;11:213-217. doi: 10.2147/CCID.S157297. PMID: 29750047; PMCID: PMC5933397.

3) Fernande G. Honfo, Noel Akissoe, Anita R. Linnemann, Mohamed Soumanou & Martinus A. J. S. Van Boekel (2014) Nutritional Composition of Shea Products and Chemical Properties of Shea Butter: A Review, Critical Reviews in Food Science and Nutrition, 54:5, 673-686, DOI: 10.1080/10408398.2011.604142.